Removal of hyperpigmentation. Evaluation of the efficacy of treatments with tranexamic acid and vitamin C- case report

Introduction. Hyperpigmentation of the skin predominantly occurs on the exposed body parts, such as the face, arms, neck, and hands, and results from the accumulation of melanin in the melanocytes visualized in the form of limited, irregular spots and patches or generalized discoloured lesions darker than the skin of an individual. Such changes may be congenital or acquired. Their most common cause is sun exposure or impaired hormone metabolism. The limited hyperpigmented lesions mainly include freckles, lentigines, chloasma (melasma), post-inflammatory, post-sun, scar and hormonal discoloration; phototoxic and photoallergic reactions.
Methods. A 44-year-old woman characterised by dry, sensitive, rather rough skin and visible capillaries, was diagnosed with hyperpigmentation lesions (post-sun patches) found on her face and arms. The course of 5 treatments was applied at 7-day intervals; each time Arkana Unitone TXA + Vit C was used involving exfoliation with AHA+BHA peelings, serum, mask and cream- a series of cosmetics with tranexamic acid, vitamin C, niacinamide and liquorice Glycyrrhiza glabra) extract.
Results. After the entire course, the size, intensity and number of patches on the face and arms were found to be reduced. Moreover, skin redness, tension and roughness were less pronounced after five treatments. The patient`s skin was smoother while the capillaries were less visible.
Conclusions. The therapy applied to even out skin tone with tranexamic acid and vitamin C resulted in the desired outcomes (i.e. reduced hyperpigmentation) and favourably affected the skin condition.

Published in 2019, 23 (2) Keywords: , ,

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Vincent Pol University in Lublin
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